Solal Quercetin
Quercetin
Indications
Quercetin is a flavonoid antioxidant extracted from fruit. It supports healthy immune function and maintains good health especially during exercise. Ordinary quercetin is not well absorbed from the intestine, however SOLAL® adds bromelain enzymes to improve absorption.
Product Composition
Each capsule contains the following active ingredients:
| Quercetin | 267mg |
| Bromelain | 35mg |
Inactive ingredients: Hypromellose (cellulose) vegetarian capsule shell (gelatine free), microcrystalline cellulose, magnesium stearate (vegetarian – flow agent), magnesium silicate, silicon dioxide and colloidal silicon dioxide.
Contains plant extracts and natural fillers, with no colourants added – therefore the colour of the capsule contents may vary slightly from batch to batch.
Sugar-free.
Dosage Directions
Adults:
Take 2 capsules in the morning and 1 capsule in the evening. This dose can be doubled under the advice of a healthcare provider.
Children under 12 years of age:
Take 1 capsule in the morning.
Product Warnings
Do not use this product if you are hypersensitive (allergic) to any of the ingredients. If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy. Do not exceed recommended dosages unless on the advice of a healthcare practitioner. This medicine has not been evaluated by the Medicines Control Council. This medicine is not intended to diagnose, treat, cure or prevent any disease.
Take special care with Quercetin if you suffer from an allergy to pineapples, as Bromelain is made from pineapples.
Side Effects
Side effects include headache, allergy, gastrointestinal upset and tingling of the extremities. Doses exceeding 6 capsules per day may be damaging to the kidney.
Special Precautions
Pineapple allergy: Individuals allergic to pineapples should use caution, as bromelain is made from pineapples.
Pregnancy & Breastfeeding
Safety in pregnancy and breastfeeding has not been established.
Interactions
Cyclosporine: Quercetin increases plasma levels and prolongs the half-life of cyclosporine.
Cytochrome P450 2C8, 2C9, 2D6, 3A4: Preliminary evidence indicated that quercetin inhibits these enzymes and this may lead to reduced elimination and higher plasma levels of medicines metabolised by these substrates.
Some medicines that could be affected include: amiodarone, docetaxel, tretinoins, repaglinide, verapamil, celecoxib, diclofenac, fluvastatin, glipizide, ibuprofen, irbesartan, losartan, phenytoin, piroxicam, tamoxifen, tolbutamide, torsemide, warfarin, amitriptyline, codeine, flecainide, haloperidol, imipramine, metoprolol, ondansetron, paroxetine, risperidone, tramadol, venlafaxine, calcium channel blockers, chemotherapeutic agents antifungals, glucocorticoids, alfentanil, fentanyl, losartan, fluoxetine, midazolam, omeprazole, lansoprazole, propranolol, fexofenadine, amitriptyline, amiodarone, citalopram, sertraline and numerous others.
P-Glycoprotein substrates: There is preliminary evidence that the quercetin inhibits the gastrointestinal P-glycoprotein efflux pump. This may increase the bioavailability and the serum levels of drugs transported by the pump. Medicines transported by the pump include: paclitaxel, diltiazem, cyclosporine, saquinavir, digoxin, chemotherapeutic agents (etoposide, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), protease inhibitors (amprenavir, indinavir, nelfinavir), H2 antagonists (cimetidine, ranitidine), verapamil, corticosteroids, erythromycin, zexofenadine, loperamide, quinidine, and others.
Quinolone antibiotics: Quercetin might competitively inhibit quinolone antibiotics by binding to the DNA gyrase site on bacteria. Quinolones include: ciprofloxacin, levofloxacin, ofloxacin, moxifloxacin, gatifloxacin and others.
